Blisters are the most common trail injury. They ruin many hikers day, or worse spoil an entire trip. Fortunately a little prevention and early attention to hot spots can usually stop a blister from forming. Blisters are fluid-filled bumps that look like bubbles on the skin. They are caused by friction, a seam in your boot, a wrinkle in your sock, sweaty or wet socks , or an ill fitting boot. Carrying a heavy pack, and hiking up hill increase the friction on the back of your heals, which makes the them the most common place people get blisters.